International Journal on Science and Technology

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Ethics, Innovation and Entrepreneurship in Biotechnology - A Systematic Review of Moral Boundaries and Entrepreneurial Decision-Making

Author(s) K. Chandra Shekar, K. Manjula
Country India
Abstract The area of biotechnology entrepreneurship is unique due to its high levels of both technical and economic uncertainty; and an elevated level of ethical awareness and concerns. Advances in genomics, gene therapy, synthetic biology, and data driven life sciences present biotech entrepreneurs with new and difficult to address ethical issues which are not limited to compliance with regulations but will influence their entrepreneurial decisions and the paths they take for innovations. While there has been extensive research on ethics and entrepreneurship separately, very little research exists on how ethics influences the decisions of biotech entrepreneurs and the paths they follow to create innovations in their biotech ventures. This paper provides a systematic review of scholarly research focusing on the relationship between ethics, innovation, and entrepreneurship in the biotechnology and life sciences industries. Using a combination of peer reviewed journals, policy reports and case studies published from 2015-2024 the systematic review identifies and integrates common themes regarding: (1) the process of establishing boundaries of morality; (2) how regulation impacts entrepreneurial behaviors; (3) how funding influences ethical considerations; and (4) how entrepreneurs can implement practices to promote responsible innovation. The results of the systematic review indicated that ethics, when considered as part of an entrepreneurial venture, may serve to constrain, shape an entrepreneur’s identity, and provide strategic direction for a biotech entrepreneur.
Keywords Biotechnology Entrepreneurship, Ethics of Innovation, Life Sciences, Moral Boundaries, Responsible Innovation
Published In Conference / Special Issue (Volume 17 | Issue 1) - One Day National Seminar on “Advances in Life Sciences for Diversity, Applications, and Human Welfare” (ALSDAHW-2025) (March 2026)
Published On 2026-03-16
DOI https://doi.org/10.71097/IJSAT.ALSDAHW-2025.127
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