Explore the Efficacy of Nanoparticles TiO₂, in Preventing and Disrupting Biofilms of Waterborne Pathogens Like Legionella Pneumophila

Author(s)	Sandeep Sahu, Anshul Chaubey, Nirbhik Karan, Dev Sharan Chaturvedi
Country	India
Abstract	This study demonstrated that TiO₂ nanoparticles synthesized via the sol-gel method were successfully produced as fine, crystalline powders with controlled nanoscale morphology, confirming their suitability for antimicrobial applications. Characterization techniques such as TEM, SEM, DLS, and FTIR collectively confirmed uniform spherical nanoparticles of approximately 15–20 nm size, with surface hydroxylation essential for photocatalytic function. The effective preparation and growth of Legionella pneumophila cultures and substantial biofilm formation set a reliable basis for evaluating antibiofilm treatments.
Keywords	Legionella pneumophila, waterborne pathogens, titanium dioxide Nanoparticles, Reactive Oxygen Species, Scanning Electron Microscopy, Transmission Electron Microscopy, Particle Size Analyzer, Dynamic Light Scattering, Biofilm
Field	Medical / Pharmacy
Published In	Volume 17, Issue 1, January-March 2026
Published On	2026-01-22
DOI	https://doi.org/10.71097/IJSAT.v17.i1.10182
Short DOI	https://doi.org/hbmh29

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