Development of Nano-emulsion Formulation of Chrysopogon Zizanioides for Targeted Antibacterial Activity Against Pyogenic Bacteria

Author(s)	Dhanyasri R P, Arun Kumar G, Kiran Kumar S
Country	India
Abstract	Chrysopogon zizanioides (Vetiver) is a medicinal plant known for its effective antibacterial activity. In the present study, we demonstrate the evidence of developing a Nanoemulsion formulation of C. zizanioides essential oil for its enhanced antibacterial activity against pyogenic infection caused by bacteria. Nanoemulsions offer improved solubility, stability, tunable rheology, optical transparency and bioavailability, making them ideal for drug delivery applications. The formulation was prepared using a high-energy emulsification method and characterized for particle size, zeta potential and stability. Antibacterial efficiency was evaluated against clinically relevant pyogenic bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, using standard microbiological assays. Results demonstrated that the Nanoemulsion formulation exhibited superior antibacterial activity compared to the crude essential oil, indicating the Nanoemulsion to be a potent antibacterial agent for treating pyogenic infections. This study highlights that the essential oil obtained from C. zizanioides serves to be a natural alternative for treating bacterial infection caused by antibiotic-resistant strain.
Field	Biology
Published In	Volume 17, Issue 2, April-June 2026
Published On	2026-04-29
DOI	https://doi.org/10.71097/IJSAT.v17.i2.10434

About IJSAT Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us	Message on WhatsApp	+91-9687-182-185	editor@ijsat.org

International Journal on Science and Technology