International Journal on Science and Technology
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Volume 17 Issue 1
January-March 2026
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The Study of Problems in Computational Genomics : A Comprehensive Review of Contemporary Challenges
| Author(s) | Mr Ravishankar Biradar, Dr. Chandan Mujamdar |
|---|---|
| Country | India |
| Abstract | Abstract Computational genomics has grown rapidly in recent years, largely driven by the widespread use of high-throughput sequencing technologies. These advances now allow researchers to examine biological systems at a much larger scale than before. However, working with genomic data is still far from straightforward. Researchers continue to face several practical and methodological difficulties during analysis and interpretation. This review discusses the major challenges currently observed in computational genomics, including high dimensionality, data heterogeneity, noisy and incomplete data, computational burden, and concerns related to model interpretability and reproducibility. The discussion also highlights recent methodological trends that attempt to address these issues. The main objective of this review is to clearly outline the existing obstacles and to encourage the development of more reliable, efficient, and biologically meaningful computational solutions. |
| Keywords | Computational genomics, high dimensionality, big genomic data, data integration, reproducibility |
| Field | Computer > Artificial Intelligence / Simulation / Virtual Reality |
| Published In | Volume 1, Issue 4, October-December 2010 |
| Published On | 2010-12-05 |
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IJSAT DOI prefix is
10.71097/IJSAT
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