International Journal on Science and Technology

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The Study of Problems in Computational Genomics : A Comprehensive Review of Contemporary Challenges

Author(s) Mr Ravishankar Biradar, Dr. Chandan Mujamdar
Country India
Abstract Abstract
Computational genomics has grown rapidly in recent years, largely driven by the widespread use of high-throughput sequencing technologies. These advances now allow researchers to examine biological systems at a much larger scale than before. However, working with genomic data is still far from straightforward. Researchers continue to face several practical and methodological difficulties during analysis and interpretation. This review discusses the major challenges currently observed in computational genomics, including high dimensionality, data heterogeneity, noisy and incomplete data, computational burden, and concerns related to model interpretability and reproducibility. The discussion also highlights recent methodological trends that attempt to address these issues. The main objective of this review is to clearly outline the existing obstacles and to encourage the development of more reliable, efficient, and biologically meaningful computational solutions.
Keywords Computational genomics, high dimensionality, big genomic data, data integration, reproducibility
Field Computer > Artificial Intelligence / Simulation / Virtual Reality
Published In Volume 1, Issue 4, October-December 2010
Published On 2010-12-05

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