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Possible Medical Intervention for Sickle Cell Disease attended to Emergency Room-White Nile State-Sudan

Author(s) Dr. Ines Belaiba Aloulou, Dr. Hutheiefa Ibrahim Y Mohammed, Dr. Hutheifa Saad Alfaki, Mr. Jasser Kacem Kacem, Ms. Yosr Aloulou, Dr. Samah M Alhussin, Dr. Suha E Mohammed
Country Sudan
Abstract Sickle cell illness included sickle cell disease, sickle cell anemia and other hemoglobinopathies included mutations for sickle cell anemia and others. Here in Sudan, sickle cell illness accumulated in different communities but vast majorities among western population, due to in door marriages, cousins, and so on. Usually lifestyle contributes in health state crisis sickle cell illness patients face, as poverty lead to malnutrition, which has consequences in red cell formation and oxygen tension later, leading to sickling crisis, pain and other complications. This study aimed to assess complete blood count, prothrombin time (PT), INR and D dimer in order to evaluate and provide descent results patients not all the time can conduct due to many reasons, financially the main. 45 sickle disease patients were involved in this study, they were SS and AS Hb types, 20 healthy subjects as control group for comparison of data. CBC conducted via hematology analyzer Mindray-BC3000, PT and INR via Quatron device –Biosystem device and reagents, D dimer through Niycocard device. Data analyzed through statistical package of social science (SPSS0 version 22. Outcome showed low Hb levels among all patients, white blood cell count varies, as well as platelet count. D dimer also fluctuated. Significant differences obtained when comparing data of case group with control group for Hb, WBC and D dimer, the rest did not.
Keywords Sickle cell disease, D dimer, hemoglobinopathies, prothrombin time
Field Biology > Medical / Physiology
Published In Volume 17, Issue 2, April-June 2026
Published On 2026-04-14
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