International Journal on Science and Technology
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Volume 17 Issue 3
July-September 2026
Indexing Partners
Rehabilitation after Intensive Care Unit Acquired Weakness: Early Mobilization, Exercise Progression and Functional Recovery - A Narrative Review
| Author(s) | Dr. Siva Bali Reddy Katasani, Dr. S Purna Chandra Shekhar, Dr. Amaresh Mohan, Dr. Sama Raju |
|---|---|
| Country | India |
| Abstract | Background: Intensive care unit–acquired weakness (ICU-AW) is a diffuse neuromuscular complication of critical illness associated with impaired mobility, delayed recovery and long-term disability. Early rehabilitation has become a major strategy for countering immobility, but intervention timing, dose and progression remain variable. Objective: To synthesize evidence published from 2012 through 2020 on physiotherapy assessment, early mobilization and exercise progression for adults with ICU-AW. Methods: A structured narrative review was conducted using peer-reviewed English-language literature published between January 2012 and December 2020. Priority was given to clinical studies, systematic reviews and consensus recommendations addressing ICU-AW, muscle wasting, mobilization safety, functional outcomes and post-ICU recovery. Results: Critical illness produces rapid muscle loss through inflammation, catabolism, disuse and impaired neuromuscular function. Early mobilization is generally feasible when delivered through interdisciplinary screening and may improve strength and mobility, although effects on mortality and long-term function are inconsistent. Reliable assessment combines arousal, Medical Research Council sum score, ICU Mobility Scale and task-based measures. Rehabilitation should progress from positioning and active participation to sitting, standing, transfers, walking and endurance training, with explicit physiological safety criteria. Conclusion: Physiotherapists play a central role in identifying ICU-AW, preventing avoidable immobility and coordinating recovery across ICU, ward and community settings. Standardized dosing and longer-term outcome studies remain priorities. |
| Keywords | intensive care unit–acquired weakness; early mobilization; physiotherapy; mechanical ventilation; critical illness; functional recovery |
| Published In | Volume 13, Issue 2, April-June 2022 |
| Published On | 2022-05-10 |
| DOI | https://doi.org/10.71097/IJSAT.v13.i2.11526 |
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Crossref DOI prefix of IJSAT is 10.71097/IJSAT
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