Chlorpheniramine Maleate against the antigenic peptide of Follicle-Stimulating Hormone Receptor (FSHR) using Insilico techniques.

Author(s)	Ms. Valleti Harshini Harshini, Ms. Pujaa B
Country	India
Abstract	Background: To use insilico techniques to examine the potential effectiveness of an anti-allergy medication against the Polycystic Ovary Syndrome (PCOS) Antigenic peptide (Model Archive: https://modelarchive.org/doi/10.5452/ma-9vhj6 ). Our present work's main objective is to dock the modeled FSHR peptide with an anti-allergy medication. The effectiveness of Chlorpheniramine Maleate against the FSHR peptide was predicted using drug docking studies. Materials and procedures: The genomic sequence of FSHR-Peptide was obtained from the UniProt database. It was then docked using the CBDOCK server with Chlorpheniramine Maleate, an anti-allergy drug currently in use. Results and Discussion: This investigation shows that the reference drug, Chlorpheniramine Maleate, interact effectively with FSHR-peptide. The compound's effectiveness against the PCOS-causing protein was evaluated using the docking score. Conclusion: The study's conclusion is that PCOS drugs effectively block the FSHR protein that is impacted. The field of endocrinology informatics research is significantly impacted by the findings of this study.
Keywords	Model Archive, CBDOCK, Discovery Studio, Estrogen Receptor 1 (FSHR), and Chlorpheniramine Maleate.
Published In	Volume 17, Issue 3, July-September 2026
Published On	2026-09-22

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