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Formulation And Evolution of Antifungal cream From Aegles Marmelos Leaves.

Author(s) Sumit Mane, Umesh Kamble, Utkarsh Patil, Shubham Patil, Priyanka Pawar, Nivedita Teli
Country India
Abstract This project focuses on the formulation and evaluation of an antifungal herbal cream containing Aegles marmelos extracts as the active ingredient to combat Candida albicans, a common fungal pathogen responsible for various infections, including oral and vaginal candidiasis. Aegles marmelos, a plant known for its medicinal properties, contains alkaloids such as atropine, scopolamine, and hyoscyamine, which exhibit antimicrobial and antifungal effects. The project aims to extract these bioactive compounds from the plant's leaves and incorporate them into a cream formulation. The creams effectiveness will be evaluated based on its ability to inhibit the growth of Candida albicans in vitro, through methods like Minimum Inhibitory Concentration (MIC) determination, and antifungal activity assays. The cream is intended to provide a topical, easy-to-apply alternative for treating fungal infections, leveraging the natural properties of Aegles marmelos for its potential therapeutic application. The study also assesses the cream's stability, pH, and skin irritation potential to ensure its safety and efficacy as a topical antifungal treatment. The overall aim of the project is to offer a sustainable, plant-based treatment option with reduced side effects compared to conventional antifungal drugs.
Keywords Aegles marmelos (Beal), Antifungal activity, MIC (minimum inhibitory concentration), cream
Field Medical / Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-04-20
Cite This Formulation And Evolution of Antifungal cream From Aegles Marmelos Leaves. - Sumit Mane, Umesh Kamble, Utkarsh Patil, Shubham Patil, Priyanka Pawar, Nivedita Teli - IJSAT Volume 16, Issue 2, April-June 2025. DOI 10.71097/IJSAT.v16.i2.3872
DOI https://doi.org/10.71097/IJSAT.v16.i2.3872
Short DOI https://doi.org/g9gds9
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