International Journal on Science and Technology

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Recent Developments in Organic Synthesis for Pharmaceutical Applications

Author(s) Dr. Seema Arora
Country India
Abstract This paper provides a comprehensive review of recent developments in organic synthesis for pharmaceutical applications in India, focusing on emerging trends, methodologies, and regulatory challenges. The importance of organic synthesis in drug development is paramount, as it supports the creation of novel therapeutic agents while ensuring cost-effectiveness and sustainability. The paper examines various synthetic techniques, including green chemistry approaches and advancements in biocatalysis, along with the integration of digital tools like computational chemistry. A critical review of secondary data reveals that while India has made significant strides in pharmaceutical synthesis, challenges persist in areas such as regulatory compliance, environmental concerns, and the need for skilled human capital. The results show that despite progress, only a fraction of Indian Small and medium pharmaceutical enterprises (SMEs) have adopted advanced green synthesis practices, and the industry struggles with regulatory hurdles, particularly in meeting international standards. The paper highlights the implications for policy, suggesting the need for stronger industry-academia collaborations, regulatory streamlining, and enhanced R&D investment. It also identifies future research directions in optimizing synthetic methods for drug discovery, scaling up innovations in biocatalysis, and adopting AI-driven technologies to improve process efficiency. These advancements are expected to position India as a global leader in pharmaceutical synthesis, contributing to the development of more affordable and effective medicines.
Field Chemistry
Published In Volume 3, Issue 4, October-December 2012
Published On 2012-12-09
DOI https://doi.org/10.5281/zenodo.15363896
Short DOI https://doi.org/g9hrsc
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