International Journal on Science and Technology

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Leveraging Nanotechnology: Innovative Strategies, Challenges, and Future Directions in Targeted Prostate Cancer Therapy

Author(s) VISHAL PANDEY, Sapna Chaudhar, Vivek Vaibhav, Zaid Anwar, Vishal Sharma
Country India
Abstract Prostate cancer is one of the most prevalent malignancies affecting men worldwide, presenting significant challenges in treatment due to its heterogeneous nature and the development of resistance to conventional therapies. This review explores the emerging field of nano therapy as a promising approach to enhance therapeutic efficacy and minimize side effects in prostate cancer treatment. By leveraging the unique properties of nanoparticles, such as targeted delivery and controlled release, nano therapy addresses critical issues associated with traditional modalities, including tumor heterogeneity and drug resistance. The mechanisms underlying nano therapy include passive and active targeting strategies, which improve drug accumulation at tumor sites while reducing systemic toxicity. Current applications of nano therapy in prostate cancer encompass innovative approaches such as hormone therapy, PARP inhibitors, immunotherapy, and PSMA-targeted therapies, alongside novel nanoparticle formulations that enhance drug delivery. Despite its potential, several challenges remain, including biocompatibility issues, regulatory hurdles, manufacturing complexities, and the need for comprehensive clinical evaluations. Looking ahead, the future of nano therapy in prostate cancer treatment is promising, driven by emerging technologies such as theranostic nanoparticles and smart nano carriers. Continued research into combination therapies and patient-centric approaches will further enhance the effectiveness of nano medicine. By addressing existing challenges and fostering collaboration among researchers, clinicians, and regulatory bodies, nano therapy has the potential to significantly improve patient outcomes and revolutionize the landscape of prostate cancer care.
Keywords Prostate cancer, nano therapy, drug delivery, targeted therapy, biocompatibility, emerging technologies
Field Chemistry > Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-05-16
DOI https://doi.org/10.71097/IJSAT.v16.i2.4875
Short DOI https://doi.org/g9kfzq
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