International Journal on Science and Technology

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A Review Article on Lipid Nanoparticles for Targeting Anti - Tumor Drugs

Author(s) Bhakti Sudha Pandey
Country India
Abstract Researchers were always coming up with new nanotechnologies to fill in gaps in the right delivery of therapeutic medications and imaging agents for Tumor therapy and diagnostics. Lipid nanoparticles, or LNPs, are acceptable particulates that are extracted from different lipids and other biochemical compounds. Their overall function is to dissolve biological barriers, or biobarriers, which enables LNPs to collect again in a specific location outside of disease-target cells for responsive therapeutics. LNPs are roughly 100 nm in size. The majority of substances with significant medicinal applications were either poisonous or insoluble in aqueous solutions, or they were unstable both chemically and physiologically. Lipid-based nanoparticles, or LBNPs, are among the most promising medication delivery systems for bioactive organic molecules. Because of its current use in chemotherapy, some chemotherapeutics have a stronger antitumor impact, revolutionizing Tumorcurement. LBNPs offer excellent temporal and thermal stability, maximum load potential, ease of preparation, low manufacturing costs, and large manufacturing output since they may be produced utilizing naturally existing sources. Additionally, combining chemotherapeutic medications with LNPs decreases curement resistance, minimizes toxicities associated with active therapeutic dosages, and increases drug concentrations in tumor cells while decreasing concentrations in normal tissue. LBNPs have been extensively researched for their potential to cureTumor, both in vivo and in vitro, with promising results in certain clinical studies. An overview of the several LBNP varieties that have been created recently, as well as their uses and contributions to various Tumorlikes, are given in this paper.
Keywords Nanotechnologies, Lipid Nanoparticles, Tumor therapy, Diagnostics, Medication delivery system, Lipid-based nanoparticles.
Field Medical / Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-05-16
DOI https://doi.org/10.71097/IJSAT.v16.i2.4978
Short DOI https://doi.org/g9kfzp
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