International Journal on Science and Technology

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Osteoarthritis Management Reimagined: Bridging Traditional Therapies with Nanotechnology and Personalized Medicine for Better Outcomes

Author(s) Swati Jirankali, Bhaskar Kurangi, Rajgouda Patil, Gururaj Kanabargi
Country India
Abstract Osteoarthritis (OA) is a leading cause of pain and disability worldwide, profoundly affecting patients’ mobility and quality of life. Traditional management strategies—such as nonsteroidal anti-inflammatory drugs, corticosteroid injections, and surgical interventions—primarily target symptom relief but often fall short in modifying disease progression and can be associated with significant side effects. Recent breakthroughs in nanotechnology have opened new avenues for OA treatment, with nanoformulations offering targeted drug delivery, prolonged therapeutic action, and minimized systemic toxicity. Innovations like liposomes, polymeric nanoparticles, and 3D-printed nanomaterial scaffolds are enabling more precise and sustained interventions, while theranostic platforms are beginning to integrate real-time diagnostics with therapy for truly personalized care. Despite these exciting developments, challenges such as manufacturing complexity, cost, and regulatory hurdles must be addressed before these technologies can be widely adopted in clinical practice. Ongoing research and well-designed clinical trials are crucial for validating the safety and efficacy of these novel approaches. Ultimately, the integration of nanotechnology and personalized medicine holds great promise for revolutionizing osteoarthritis management, offering hope for improved outcomes and a better quality of life for patients.
Keywords Osteoarthritis, nanotechnology, nanoformulations, personalized medicine, theranostics
Field Medical / Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-05-27
DOI https://doi.org/10.71097/IJSAT.v16.i2.5723
Short DOI https://doi.org/g9mvt7
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