
International Journal on Science and Technology
E-ISSN: 2229-7677
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Volume 16 Issue 2
April-June 2025
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Eutectic Mixtures: Bridging Physicochemical Fundamentals and Technological Applications
Author(s) | Vishal I. Wannur, Archana S. Patil |
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Country | India |
Abstract | Eutectic mixtures are unique multi-component systems that melt at a temperature lower than their individual constituents, offering distinct advantages in various scientific and technological domains. This review explores the fundamental principles governing eutectic systems, with emphasis on phase behavior, thermodynamic interactions, and structural characteristics. The article highlights the pharmaceutical potential of eutectic mixtures in enhancing the solubility, dissolution rate, and bioavailability of poorly water-soluble drugs, thereby improving oral and topical drug delivery. Applications in controlled drug release and dermal formulations are thoroughly discussed. Beyond pharmaceuticals, eutectic systems have found valuable applications in materials science, especially in alloy production, phase change materials, and eco-friendly solvents. Recent advances in deep eutectic solvents (DES) and natural deep eutectic solvents (NADES) showcase their promise as sustainable alternatives in green chemistry. The review also discusses characterization methods such as differential scanning calorimetry (DSC), Powder X-ray Diffraction (PXRD), and Fourier-transform infrared spectroscopy (FTIR), essential for analyzing eutectic behavior and interactions. Overall, eutectic mixtures represent a dynamic and versatile class of systems with broad implications for drug delivery, chemical processing, and materials innovation. |
Keywords | Eutectic mixture, Deep Eutectic Mixture, Controlled Drug Release, X-Ray Powder Diffraction, Differential Scanning Calorimetry |
Field | Medical / Pharmacy |
Published In | Volume 16, Issue 2, April-June 2025 |
Published On | 2025-06-05 |
DOI | https://doi.org/10.71097/IJSAT.v16.i2.6017 |
Short DOI | https://doi.org/g9pz6s |
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IJSAT DOI prefix is
10.71097/IJSAT
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