Carcinogenic Potential of Repeatedly Heated Vegetable Oils: Mechanisms, Evidence, and Future Directions

Author(s)	Syed Basit
Country	India
Abstract	This paper evaluates the carcinogenic potential of repeatedly heated vegetable oils (RHVOs). Animal based studies have shown that consumption of RHVO induces oxidative stress, early tumor development and cellular damage in hepatic and intestinal tissues; increased lipid peroxidation, histopathological abnormalities and altered antioxidant enzyme profiles has been observed in animals fed on RHVO [5]. Critical reviews highlight the generation of polycyclic aromatic hydrocarbons (PAHs), and other genotoxic agents in overheated oils and their fumes which further links the RHVO exposure to higher risks of lung, prostrate, colorectal and breast cancer [3][8]. Meta-analysis of general vegetable oil consumption has not shown any significant link with the breast cancer risk, this emphasis the distinction between unheated and thermally degraded oils [7]. This study underscores the need for public awareness around oil reuse practices in commercial and domestic cooking, to mitigate potential carcinogenic risks.
Field	Biology > Medical / Physiology
Published In	Volume 16, Issue 3, July-September 2025
Published On	2025-07-17
DOI	https://doi.org/10.71097/IJSAT.v16.i3.7072
Short DOI	https://doi.org/g9t2wz

About IJSAT Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us	Message on WhatsApp	+91-9687-182-185	editor@ijsat.org

International Journal on Science and Technology