To Evaluate the Effect of Acupuncture in the Subjects with Mild to Moderate Anxiety and Depression

Sandeep. S; AFREEN; ARCHANA N; ASHWINI; BHAGAVAN REDDY; BHAGYA M; BHOOMIKA B V; MAHADEV ROTTI; MEGHANA K A; YASHASWINI K B

To Evaluate the Effect of Acupuncture in the Subjects with Mild to Moderate Anxiety and Depression

Author(s)	Dr. Sandeep. S, AFREEN, ARCHANA N, ASHWINI, BHAGAVAN REDDY, BHAGYA M, BHOOMIKA B V, MAHADEV ROTTI, MEGHANA K A, YASHASWINI K B
Country	India
Abstract	Anxiety and depressive disorders are among the most prevalent mental health conditions globally and are significant contributors to the overall burden of disease and disability (1). Both disorders substantially impair quality of life (2). Depression is characterized by a persistent feeling of sadness and a loss of interest in daily activities (6), whereas anxiety is associated with fear and manifests as a future-oriented mood state involving complex cognitive, affective, physiological, and behavioral responses (8). These conditions not only compromise psychosocial well-being but also increase the risk of chronic physical illnesses, including cardiovascular and metabolic disorders (Penninx et al., 2021). Depressive disorders commonly present with sadness, emptiness, or irritability, accompanied by somatic and cognitive changes that significantly reduce an individual’s functional capacity (13). Although anxiety and depression are distinct syndromes, there is substantial overlap in clinical symptoms and underlying pathophysiological processes. Comorbid anxiety and depression are more prevalent than either condition alone, with studies showing that 58% of individuals with a history of depression also meet criteria for an anxiety disorder. The World Health Organization has also identified anxiety and depression as the most common coexisting psychological problems in primary care settings. Dysregulation of serotonin and norepinephrine neurotransmission has been implicated in both disorders, and emerging evidence suggests that these systems may provide a mechanistic link between them, with disturbances in one system reflecting in the other. Current theories propose a continuum of illness, suggesting that anxiety and depression may represent different phenotypic expressions of a shared neurobiological origin (32).
Field	Medical / Pharmacy
Published In	Volume 16, Issue 4, October-December 2025
Published On	2025-10-06

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To Evaluate the Effect of Acupuncture in the Subjects with Mild to Moderate Anxiety and Depression

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