International Journal on Science and Technology

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Comparison of the Wintrobe Method with the Westergren Method for the Estimation of Erythrocyte Sedimentation Rate (ESR)

Author(s) Mr. SANJEEV AHIRWAR, Ms. ALEMA KHAN, Mr. MD MASUD AZAHAR
Country India
Abstract Abstract
Background: Erythrocyte Sedimentation Rate (ESR) is a widely used hematological test for detecting inflammation and monitoring disease progression. Among the various methods for ESR determination, the Wintrobe and Westergren methods are commonly employed. This study aims to compare the accuracy, precision, and clinical applicability of the Wintrobe and Westergren methods for ESR estimation.
Materials and Methods: Blood samples from 100 subjects were collected in EDTA anticoagulant tubes. ESR was measured using both Wintrobe and Westergren methods. Data were analyzed using mean, standard deviation, and correlation coefficients to assess agreement between the two methods.
Results: The mean ESR values obtained by the Wintrobe method were slightly lower than those obtained by the Westergren method. Statistical analysis revealed a strong positive correlation (r = 0.87, p < 0.001) between the two methods. However, the Westergren method consistently demonstrated higher sensitivity in detecting elevated ESR levels.
Conclusion: Both methods are reliable for ESR estimation; however, the Westergren method remains the gold standard due to its higher sensitivity and broader clinical applicability. The Wintrobe method may be useful in resource-limited settings or for rapid screening.
Keywords ESR, Wintrobe method, Westergren method, Hematology, Inflammation
Field Biology > Medical / Physiology
Published In Volume 16, Issue 4, October-December 2025
Published On 2025-11-19
DOI https://doi.org/10.71097/IJSAT.v16.i4.9509
Short DOI https://doi.org/hbb8gm
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