International Journal on Science and Technology

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Formulation and Evaluation of Syrup by using Papaya Leaf Liquid Extraction for Treatment of Thrombocytopenia

Author(s) Rutuja Rahul Hajare
Country India
Abstract Thrombocytopenia is a clinical manifestation that refers the platelet count I.e., <150 10/UL, of Blood, resulting in imbalanced hemostasis which leads to several fatal complications. The causative factors very great, but as a consequence, they interfere with platelet production and promote destruction, leading to death. Carica Papaya leaf has unique therapeutic and medicinal characteristics against thrombocytopenia, and this is supported by scientific studies. Secondary metabolites and minerals in the leaf, such as carpaine and queroetin, promote platelet production, inhibit platelet distruction and maintain platelet membrane through gene expression activity and the oesing of viral professes respectively. This review explores the scientific studies the support the role of papaya leaf in the form juice, liquid extract of syrup, extract of powder against thrombocytopenia through animal modeling and clinical trials. Phytochemicals profiles of C.Papaya leaf revealed the presence of flavonoids, alkaloids, phenols, cardiac glycosides, tannins, terpines, and saponins, which impact therapeutic potential to the leaf. The therapeutic benefits of the leaf The therapeutic benefits of the leaf include immunomodulatory, antiviral, antidibetic, anticancer, antimalarial, antiglogenic, antibacterial, and antioxidant activities, several conducted scientific research studies have proved the efficacy of C. papaya leaf against thrombocytopenia, expanding the implication of natural sources to eradicate numerous aliments.
Keywords Keywords: - thrombocytopenia, carica papaya leaf, phytochemicals, gene expression activity, therapeutic potential
Field Medical / Pharmacy
Published In Volume 16, Issue 2, April-June 2025
Published On 2025-06-25
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